The Premier Breakthroughs 2025 Conference—set against the backdrop of rapid transformation in the healthcare landscape—brings together influential voices in medicine, neuroscience, public policy, supply chain strategy, and athletic advocacy. Hosted by Premier Inc., this year’s event features a powerful speaker lineup that exemplifies the conference’s theme: “Innovating Resilience: Leading Healthcare Forward.”

“Digital health technologies empower patients to monitor and manage their health, improving medication management and access to therapies.” — Michael J. Alkire

Michael J. Alkire – President & CEO, Premier Inc.

As the guiding force behind Premier Inc., Michael J. Alkire continues to redefine what’s possible in integrated healthcare performance. His leadership focuses on integrating clinical, financial, supply chain, and operational performance solutions, enabling member hospitals and health systems to achieve sustainable improvements in quality and cost. Under his stewardship, Premier leverages one of the nation’s largest comparative outcome databases, enabling evidence-based decision-making and accelerating performance across its alliance of providers.

At Breakthroughs 2025, Alkire underscores the urgent need for data-driven collaboration to meet modern healthcare demands. He highlights Premier’s latest innovations in labour, supply chain, and safety applications—tools that are increasingly indispensable in the face of staffing shortages, inflation, and global disruptions. Alkire’s vision is focused on empowering healthcare providers with actionable insights, so they can deliver more equitable, efficient, and patient-centred care in an ever-evolving landscape.

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Andrew Huberman – Neuroscientist & Host, Huberman Lab Podcast

Dr. Andrew Huberman brings groundbreaking insights from the frontier of neuroscience. A professor at Stanford School of Medicine, Huberman’s work on brain plasticity and cognitive function has revolutionized how we understand the human capacity to adapt, learn, and heal. At Breakthroughs 2025, he will explore how neuroscience can unlock improved health outcomes, particularly in high-pressure clinical environments.

Huberman’s keynote draws a vital connection between brain science and healthcare delivery, demonstrating how stress, sleep, and focus influence decision-making and patient care. Through his widely followed Huberman Lab Podcast, he has translated complex scientific discoveries into practical strategies for enhancing mental and physical performance. His message resonates deeply with health professionals seeking to optimize both personal resilience and organizational well-being.

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Geeta Nayyar, M.D., M.B.A. – Physician, Technologist & Author

Dr. Geeta Nayyar stands at the intersection of clinical excellence and technological transformation. As the former Chief Medical Officer at Salesforce and AT&T, she brings unique expertise in harnessing AI, automation, and digital tools to humanize healthcare. Her bestselling book and global advocacy underscore a commitment to aligning innovation with empathy and trust.

In her session, Nayyar explores how health leaders can integrate emerging technologies without losing the personal touch that defines patient care. She challenges systems to view digital transformation as a tool for connection, not disruption. With a warm, incisive approach, she lays out a roadmap for balancing tech adoption with clinical compassion, fostering better outcomes for both patients and providers.

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Simone Biles – Athlete & Advocate

Simone Biles, the most decorated gymnast in history, brings a message of courage, discipline, and mental health advocacy to Breakthroughs 2025. With 41 World Championship and Olympic medals, Biles has long been a symbol of excellence. But it’s her decision to prioritize her mental well-being on the global stage that cemented her role as a transformative figure beyond athletics.

“Our brains are plastic, and we have the ability to change and shape them throughout our entire lives.” — Andrew Huberman

In an intimate conversation, Biles speaks about the pressures of elite performance, the importance of mental health in high-stakes environments, and how healthcare professionals can better support holistic wellness. Her powerful story resonates with clinicians and leaders alike, offering inspiration on how to create systems that allow individuals, not just athletes, to thrive without sacrificing their humanity.

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Bruce Radcliff – SVP of Supply Chain, Premier Inc.

With over 25 years of healthcare and supply chain experience, Bruce Radcliff is reshaping how health systems think about procurement, sourcing, and logistics. Since joining Premier in 2023, he’s injected fresh momentum into its group purchasing and strategic sourcing divisions, ensuring that supply chain strategies are aligned with frontline realities.

Radcliff’s session focuses on driving competitiveness and resilience through innovative sourcing models and advanced analytics. He offers a provider-informed perspective that resonates with attendees who understand the stakes of every product and contract decision. By bridging the gap between operational goals and patient impact, Radcliff sets a high standard for what a modern healthcare supply chain can—and must—achieve.

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Soumi Saha, PharmD, JD – SVP of Government Affairs, Premier Inc.

Dr. Soumi Saha is a powerful advocate for healthcare providers navigating complex regulatory landscapes. Blending pharmaceutical and legal expertise, she leads Premier’s policy efforts to strengthen healthcare delivery and supply chain resilience. Her work has directly influenced legislation like the MEDS Act, which has improved national preparedness for drug shortages.

At Breakthroughs 2025, Saha shares strategies to amplify the provider voice in Washington, D.C., and accelerate policies that safeguard patients and streamline care delivery. Her insights are especially critical in the wake of the COVID-19 pandemic, as healthcare systems grapple with persistent vulnerabilities. Saha champions a future in which providers drive meaningful change through informed, proactive advocacy.

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Conclusion

Together, these leaders represent the convergence of science, care, policy, and purpose—an essential mix for navigating the next era of healthcare. Premier Breakthroughs 2025 is not just a conference—it’s a call to lead, connect, and transform.

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